NASA
is committed to maintaining astronaut health during exploration
missions. The maintenance of astronaut health and fitness during
space missions is important to ensure the accomplishment of
critical mission tasks in transit to and from the moon and Mars
as well as on the lunar and Martian surfaces. Muscles and bones
weaken as an adaptation to reduced gravity environments, and
no exercise regimen has been effective in successfully combating
these effects.
The Exercise Physiology and Countermeasures
Project (ExPC) at NASA’s Glenn Research Center supports the
lead project office atNASA’s
Johnson Space Center in developing exercise countermeasure prescriptions
and exercise devices for space exploration that are effective, optimized,
and validated to meet medical, vehicle, and habitat requirements.
A countermeasure is a therapy, procedure or device used to prevent
or minimize adverse health effects that could result from spaceflight,
such as bone loss or weakened muscles. An exercise countermeasure
prescription is a set of instructions for exercise that include
which exercise device to use as well as how long, how often and
how strenuously to use it. The prescription also measures the effectiveness
of the exercise as a countermeasure.
Enhanced Zero Gravity
Locomotion Simulator Videos
Click on the images
below to view videos
eZLS Exercise Video
(Part 1)
eZLS Exercise Video
(Part 2)
eZLS Exercise footage
Astronaut
Don Thomas Interview
Dr. Peter Cavanagh
Interview, Co-Director, Center for Space Medicine Cleveland
Clinic
eZLS Exercise, additional
footage
Exercise
Physiology and Countermeasures Project at Glenn Research Center
Exercise Countermeasures
Project at GRC video
National Space Biomedical
Research Institute (NSBRI) study – “Monitoring Bone Health
by Daily Load Stimulus Measurement During Lunar Missions”
Enhanced Zero-g Locomotion Simulator (eZLS) at GRC in the 9.5
degree head-up pitch position to simulate the 1/6th gravity of
the lunar surface
Test subject completing the ‘ladder climb’ task
in simulated lunar gravity
Overview:
Dr. Peter R. Cavanagh is leading a project to develop and validate a miniaturized
accelerometer-based system that could be worn by astronauts to collect data
on how much load stimulus is put on the lower body each day and to interpret
the information in relation to bone health. After validation, the final product
- the Accelerometric Daily Load Sensor - will consist of a small shoe-mounted
sensor that will transmit signals to a BioWATCH, a device that can collect,
store and transmit data on many human body systems. Software in the spacecraft
or lunar habitat will read the data to determine how much more exercise is
needed to maintain bone health.
One of the key questions that remain unanswered as we prepare for prolonged lunar
sojourns is the degree to which living and exercising on the lunar surface will
provide an osteoprotective stimulus to prevent the loss of bone mineral that
has been observed in microgravity. The concept of daily load stimulus is useful
in this regard since it has the potential to estimate the "dose" of
load to the lower extremities that will maintain skeletal integrity even in the
setting of concurrent therapeutic drug and exercise countermeasures. Most observers
believe that some form of supplementary exercise will be required during lunar
activity, but this will need to be optimized to provide the most efficient use
of crew time.
We are in the process of developing and validating a miniaturized, accelerometer-based
system that could be used during intravehicular and extravehicular activity on
the lunar surface to monitor the complete daily load stimulus to the lower extremity
and interpret that information in relation to bone health. After validation in
the enhanced Zero Gravity Locomotion Simulator (eZLS) at NASA Glenn Research
Center and the lunar bedrest analog at the University of Texas Medical Branch,
a deliverable of this project will be a system, the Accelerometric Daily Load
Sensor (aDLS), including a small shoe-mounted unit that will transmit signals
to a portable data logger that could potentially be used to collect data on other
physiological systems simultaneously. Onboard software with visual feedback will
determine how much additional exercise is required each day to maintain bone
homeostasis. This high Technology Readiness Level project combines theory, experimentation
and hardware development to produce a device that will be a critical component
in the effort to maintain bone health during lunar missions. The project is a
collaborative effort between the University of Washington, the Exercise Countermeasures
Laboratory at NASA Glenn Research Center, ZIN Technologies and the University
of California, San Francisco.
Earth-based Applications of Research
Project
Athletic communities, the aging population,
osteoporotic patients and elderly care personnel could use this accurate
and detailed ambulatory activity-monitoring system that has the added
benefit of software that predicts bone health. This project has the
potential to produce a NASA spin-off that would benefit the mentioned
populations through personal bone health monitoring systems. In 2005,
osteoporosis-related fractures in the U.S. were responsible for an
estimated $19 billion in medical expenses. This estimate is expected
to rise to $25.3 billion by 2025. The personal monitoring system being
developed under this grant can help individuals manage their bone
health based on personal exercise goals and real-time feedback. Use
of this hardware could help significantly decrease medical costs related
to osteoporotic fracture.
Harness Station Development Test Objective
(Harness SDTO)
A
new exercise harness for crew members on the International Space
Station (ISS) has been developed out of the Center for Space Medicine
(CSM), a NASA Glenn/Cleveland Clinic collaboration. The CSM harness
will be evaluated during on-orbit exercise in a Station Development
Test Objective (SDTO). Treadmill exercise has been used on orbit
since early space shuttle flights because it has the potential to
simultaneously benefit the neurovestibular, musculoskeletal, and
cardiovascular systems. Extensive effort has been put forth toward
the development of exercise countermeasures, yet bone continues
to be lost on current ISS missions and is a major concern for future
exploration missions. A treadmill with vibration isolation (TVIS)
has been a major component of the exercise hardware on the ISS.
However, it has not proven to be a successful countermeasure. The
key to the success of load-bearing exercise in space, such as treadmill
running, is the application of loads to the crew member via a subject
load device coupled to the body by a harness. ISS crew members frequently
report discomfort from the current types of exercise harnesses,
which makes the exercise protocols less effective. Experiments on
the ISS have shown that this has resulted in low ground reaction
forces on orbit (approximately 60 percent of 1-g loads), which is
likely to be a major factor in the observed loss of bone mineral
density in crew members. This project utilized valuable insights
from the backpack industry for harness configuration and distributing
loads to develop an improved harness for flight. The harness is
designed to better distribute loads at the shoulders and hips and
to accommodate for individual differences, including gender. The
project resulted in the advancement of a new, more comfortable harness
design that has been developed for flight testing on the ISS.
This Station Development Test Objective (SDTO) assesses whether
crew members can exercise more comfortably and at higher loads using
a new treadmill harness, as compared to the existing ISS treadmill
harness. The hypotheses are as follows: (i) the CSM harness will
provide greater overall comfort than the current ISS treadmill harness;
(ii) crew members will be able to tolerate higher external loads
from the subject load device; (iii) load distribution measurements
collected with strain gauge instrumentation (buckle transducers)
between shoulders and hips will correlate with subjective measures
of comfort; and (iv) the CSM harness will provide more effective
wear and adjustability (easier adjustments, and adjustments will
stay fixed once they are set, breathable biocide outer fabric).
The SDTO research protocol is aimed at improving comfort, plus increasing
consistent loading for crew members exercising on the ISS treadmill(s).The
CSM harnesses will be instrumented to allow for objective correlation
with subjective ratings of comfort. To provide a direct comparison
with the ISS treadmill harness, the load distribution and subject
load device applied to the ISS treadmill harness will also be measured.
The ISS treadmill harnesses will be instrumented by the crew on-orbit
during a one-time setup activity. Previously, measurement of inflight
load distribution of the harness or the applied external load has
not been performed—these objective data sets may be correlated
with subjective comfort data for improved designs and for existing
and advanced concept exercise countermeasures systems requiring crew
member harnessing.
The sensors to measure load distribution were
developed during pilot testing of the prototype harness. This load
sensing methodology will be used during the flight experiment to
obtain comparisons of load and comfort between the new CSM harness
and the current U.S. ISS harness.
Development of optimized crew equipment
for exercise is highly relevant to the ISS and Human Research Programs.
The intended outcome of the SDTO is qualitative and quantitative
data to demonstrate that crew members prefer the fit and function
of the CSM harness, and are able to tolerate higher subject loading
during treadmill exercise aboard the ISS. Loading through the subject
load system approaching 1-g-like loads (one bodyweight) is thought
to be more effective for maintaining musculoskeletal health on-orbit.
A second intended outcome is that the design and/or design elements
identified as desirable improvements will be implemented as new operational
hardware (harness/bungee) requirements for treadmill exercise. Furthermore,
the crew member responses to directed questions relating to comfort,
ease of use, wear, and durability will provide insight to improvements
that may be made for future flight harness designs.
To meet these objectives, Glenn has developed the enhanced Zero-gravity
Locomotion Simulator (eZLS), which is a new ground-based simulator
developed to address the detrimental physiological effects of
spaceflight on the musculoskeletal system through improved exercise
countermeasure systems. The eZLS has the ability to mimic
the vehicle and exercise device interfaces found on the International
Space Station (ISS) and other vehicles being developed for future
space exploration. It is important to replicate the interface
configurations seen on the ISS and future vehicles to understand
how the interface may affect the resulting forces on the muscles
and bones. The eZLS is also a test bed for future exploration
missions and can be used to simulate locomotion in partial gravity
environments including the moon and Mars.
In an effort to develop improved exercise routines
and equipment for astronauts, the eZLS allows scientists and engineers
to conduct research with human participants in the following areas:
Understanding the metabolic cost of locomotion
in partial gravity
Improving crew comfort during exercise
Developing exercise prescriptions
Optimizing hardware
Developing and characterizing advanced exercise
device concepts for exploration missions
Aside from space applications, experiments conducted
using the eZLS may help medical researchers improve their understanding
of the role of exercise in the prevention of osteoporosis on Earth.
The deterioration of bone and muscle during osteoporosis is similar
to what occurs in an astronaut’s body, although the process
is greatly accelerated in space.
Advanced Exercise Concepts
Glenn’s Exercise Physiology and Countermeasures Project is also
performing simulations of locomotion in lunar gravity to assess the
physiological demands of performing critical mission tasks such as
carrying equipment and recovering from a fall on the moon. Since the
critical mission task assessments will require the cooperation of
different laboratories in other locations, Glenn is developing a database
to store, process, and archive the physiological data collected from
these assessments.
Advanced Exercise
Concepts video
The Orion crew exploration vehicle, lunar lander,
and/or lunar habitats may also have exercise equipment to keep crewmembers
healthy and fit for duty. Glenn’s Exercise Physiology and
Countermeasures Project is developing advanced exercise device concepts
to meet the requirements for exploration missions. There are special
challenges posed by providing equipment with adequate capability
while meeting volume, mass and power limitations imposed by the
vehicle or habitat.
Advanced
Exercise Concepts video
Apollo astronauts are providing valuable insight
regarding the benefits of exercise and the limitations of the equipment
they used during the Apollo missions. When this information is combined
with the critical mission task assessment data, the results will aid
in the development of new advanced concept equipment designs and exercise
prescriptions for exploration missions.